Alzheimer’s disease

Beyond Memory Loss: A Surprising Early Sign of Alzheimer’s

by

New research from Texas A&M Health indicates that cognitive flexibility—the brain’s ability to adapt to changing rules and unexpected situations—may decline months before traditional memory loss symptoms appear in Alzheimer’s disease. Published in Nature Communications, the study suggests that identifying these executive function deficits could provide a critical window for earlier clinical intervention. Executive Function … Read more

Myelin Damage and Sleep: How It Disrupts Brain Rhythms

by

Researchers at the Netherlands Institute for Neuroscience have identified a link between myelin sheath degradation and abnormal brain activity during sleep, potentially providing a new non-invasive biomarker for neurodegenerative diseases. According to research presented at the Federation of European Neuroscience Societies (FENS) Forum 2026, myelin damage triggers epilepsy-like electrical spikes and disrupts critical oscillations exclusively … Read more

New Drug Reduces DNA Damage and Inflammation in Alzheimer’s Model

by

Researchers have identified a potential therapeutic pathway for Alzheimer’s disease by targeting DNA damage within brain neurons. A study published in FEBS Open Bio reports that the molecule KCL-286 successfully repairs neuronal DNA in mouse models, simultaneously reducing brain inflammation and abnormal immune activity associated with neurodegeneration. How does KCL-286 target Alzheimer’s disease? The drug … Read more

How to Prevent Dementia: The Science-Backed Guide

by

Intensive lifestyle interventions, such as those tested in the FINGER and POINTER clinical trials, produce only modest improvements in cognitive performance and have not yet been shown to reduce the incidence of dementia. According to the 2024 Lancet Commission report, 45% of global dementia cases could — in theory — be prevented based on 14 … Read more

BCG Vaccine May Alter Human Brain Immunity

by

The Bacillus Calmette-Guérin (BCG) vaccine, typically used to prevent tuberculosis, may remodel the brain’s immune environment to potentially lower Alzheimer’s disease risk, according to research published in Communications Medicine. A year-long study led by Mass General Brigham investigators found the vaccine increased immune cell responsiveness and altered Alzheimer’s-related biomarkers in older adults without pre-existing pathology. … Read more

Parkinson’s Disease: Women Show Higher Amyloid Plaque Levels Than Men

by

Women diagnosed with Parkinson’s disease exhibit a higher amyloid plaque burden in the brain compared to men, according to a study led by the Mayo Clinic Arizona. While men with Parkinson’s are generally at a higher risk of developing dementia, this new research indicates that women harbor more Alzheimer’s-related protein deposits, even when adjusting for … Read more

High-Dose DHA Fails to Boost Memory Despite Brain Penetration

by

High-dose docosahexaenoic acid (DHA) supplementation successfully increases omega-3 levels in the human brain but fails to halt cognitive decline or structural brain changes, according to a randomized clinical trial published in eBioMedicine. Researchers monitored 365 older adults over two years, finding that while the supplement reached the central nervous system, it provided no measurable benefit … Read more

How Psychological Traits Influence Alzheimer’s Biology

by

Long-standing psychological traits, including neuroticism and a lack of purpose, track distinct molecular pathways in Alzheimer’s dementia, according to a multi-omics study published in Translational Psychiatry. Researchers from the Religious Orders Study (ROS) and the Rush Memory and Aging Project (MAP) found that while traditional pathology and genetic risk factors identify overall disease susceptibility, these … Read more

AI Discovers Novel Antibiotics Within Disease-Causing Prions

by

Researchers at the University of Pennsylvania have identified a new class of potential antibiotics hidden within prions, the misfolded proteins typically associated with fatal neurodegenerative conditions. By using the deep-learning platform APEX 1.1 to scan 19.3 million protein fragments, the team discovered 1,179 antimicrobial candidates—dubbed “prionins”—that can kill drug-resistant bacteria, according to findings published in … Read more

Brain Health Awareness Gaps Among Older Adults Revealed

by

Less than half of Michigan adults aged 50 and older know that daily lifestyle choices can reduce dementia risk, according to the Michigan Poll on Healthy Aging. While most residents value brain health, a significant gap exists between their intentions and their actual daily habits regarding sleep, diet, and physical activity. Why is there a … Read more

© 2026 Newsy Today. All rights reserved.


For contact, advertising, copyright, issues email: [email protected]

For contact, advertising, copyright, issues email: [email protected]