City of Hope investigators have formulated an innovative plug-and-play technique that incorporates engineered molecules into chimeric antigen receptor (CAR) T cells post-treatment, based on findings shared this month in Cancer Immunology Research, an American Association for Cancer Research journal. The preclinical study offers a flexible approach to help CAR T cells keep pace with mutating … Read more
Senior actress Yurike Prastika overcame stage four breast cancer that metastasized to her spine, according to her public statements at Studio Trans TV in Tendean, Jakarta Selatan, on September 18, 2026. The 58-year-old artist shared details of her medical journey, including the initial discovery of a large lump, the rigorous combination of chemotherapy and radiation, … Read more
Adding local consolidative therapy after induction treatment with nivolumab plus ipilimumab does not improve overall survival or progression-free survival in patients with metastatic non-small cell lung cancer, including those with oligometastatic disease, according to phase III trial results presented at the International Association for the Study of Lung Cancer 2026 World Conference on Lung Cancer. … Read more
Food and Drug Administration this week to test genetically engineered CAR T-cell immune cells in adults with advanced colorectal cancer and pediatric patients with solid tumors, according to university announcements. The experimental therapy attacks two specific targets, B7-H3 and IL-8, aiming to overcome the defenses of solid tumors where standard treatments have failed. University of … Read more
Aging brain biology actively shapes brain tumor progression, treatment resistance, and cognitive decline, according to a review published in Ageing and Cancer Research & Treatment. Rather than viewing aging as a passive background variable, the study—titled “Navigating the aging brain: The interplay between brain malignancy and the aging microenvironment”—proposes that the physiological shifts of an … Read more
Hepatocellular carcinoma, currently the sixth most common malignancy and the third leading cause of cancer-related death globally, is facing a paradigm shift in precision management according to a comprehensive review published in Cancer Biology & Medicine. Researchers from the Eastern Hepatobiliary Surgery Hospital at Naval Medical University in Shanghai and the First Affiliated Hospital of … Read more
Researchers at Ludwig Princeton have discovered that tumors can manipulate distant organs to evade the immune system, according to a study published in Cell Metabolism. Led by Yibin Kang and Yong Tang, the research demonstrates how cancer cells send signals across the body to alter fat metabolism in the liver and immune responses in CD8⁺ … Read more
Rare CD4 cytotoxic T lymphocytes reach strikingly high levels in people who live beyond 110, revealing an unusual pattern of clonal expansion and functional flexibility, according to a study published in the journal Cell Reports. Researchers characterising these immune cells found that supercentenarians maintain immune profiles that exhibit advanced differentiation without the typical markers of … Read more
According to research published in EMBO Molecular Medicine by teams at Adelaide University and the Olivia Newton-John Cancer Research Institute, a molecular switch driven by low levels of the naturally occurring molecule miR-342 and high activity of the E2F pathway fosters metastatic triple-negative breast cancer. While this aggressive subtype accounts for 10 to 15 percent … Read more
According to research published in the Chinese Medical Journal, a mitochondrial matrix protein known as RTN4IP1 drives the progression and metastasis of triple-negative breast cancer by disrupting cellular energy metabolism. Triple-negative breast cancer accounts for roughly 15% of all breast cases and lacks estrogen, progesterone, and HER2 receptors, leaving patients with high risks of recurrence … Read more