A therapeutic approach for multiple sclerosis developed at Johannes Gutenberg University Mainz is moving toward clinical application, backed by a EUR 1.1 million funding boost from ForTra gGmbH for Research Transfer, according to university announcements on September 1, 2026. ForTra Funding Drives GMP Production and Phase I Trials ForTra gGmbH for Research Transfer, a nonprofit … Read more
According to a study published on August 7, 2026, in Volume 17 of Oncotarget, treatment with the multi-kinase inhibitor K252a transiently delayed the growth of SK-ES-1 Ewing sarcoma tumor xenografts in immunodeficient mice. Led by researchers at the Federal University of Rio Grande do Sul and INCT BioOncoPed in Brazil, the team found that the … Read more
Researchers at The University of Texas at Austin have developed an experimental drug that tricks aggressive cancer cells into consuming more sugar than usual while simultaneously blocking their backup fat metabolism. According to a study published in Nature Chemical Biology, the compound successfully treated an aggressive form of melanoma in mice by attacking both cellular … Read more
Researchers have identified a new chemical compound, DE19725241, that shows potential in targeting the fat mass and obesity-associated protein (FTO) to treat pancreatic cancer. According to a study published in BIO Integration, the compound demonstrated selective antiproliferative activity in pancreatic cancer cell lines by binding to specific protein sites, offering a potential new scaffold for … Read more
Researchers at the University of Massachusetts Amherst have developed an artificial intelligence model called MycoPermeNet to accelerate the discovery of tuberculosis drugs. By combining this AI with a high-throughput screening technique known as PAC-MAN, the team can predict which chemical compounds can penetrate the bacterium’s unique mycomembrane, potentially speeding up the search for effective treatments … Read more
Breakthrough in Antibiotic Resistance: Targeting Bacterial Enzymes How the Study Uncovered a New Approach Antibiotic resistance, a global health crisis linked to 4.7 million deaths in 2019, has seen a critical breakthrough. Researchers at Scripps Research discovered that disabling a bacterial enzyme called secreted antigen A (SagA) makes vancomycin-resistant Enterococcus faecium (VREfm) vulnerable to vancomycin. … Read more
Exposure to glyphosate, the active ingredient in many weed killers, is linked to changes in hormones that support pregnancy and fetal development, according to a University of Michigan School of Public Health study. Researchers observed shifts in estriol, thyroid hormones, and corticotropin-releasing hormone among 752 pregnant women in Puerto Rico. How does glyphosate exposure affect … Read more
Monash University researchers found that the copper compound Cu(ATSM) increases brain clearance pumps by 24.1%, reducing toxic amyloid-beta proteins by 42%. According to a study published in ACS Chemical Neuroscience, this treatment repairs the blood-brain barrier and improves spatial learning by nearly 44% in Alzheimer’s disease models. How does Cu(ATSM) repair the brain’s waste-clearing system? … Read more
Researchers at ETH Zurich have identified a new chemical compound, dubbed “Compound 10,” that shows potential in slowing the progression of Alzheimer’s disease by targeting the enzyme GRK2. According to findings published in Cell Reports Medicine, the substance prevents the formation of harmful enzyme aggregates in brain cells, offering a distinct mechanism compared to existing … Read more
The Dawn of the Single-Encounter Radical Cure: Redefining Malaria Treatment For decades, the fight against malaria has been a game of attrition. We treat the symptoms, we clear the blood, but the parasite often finds a way to hide, waiting in the liver to trigger a relapse. However, a breakthrough in chemical engineering is shifting … Read more