Midlife Brain Aging Linked to Immune Cells and Blood-Brain Barrier Decline

New data from a National Institutes of Health-funded study reveals that midlife brings substantial remodeling to the immune cell landscape of the human hippocampus, pointing to a potential mechanism behind chronic neuroinflammation in neurodegenerative diseases. Scientists analyzed postmortem hippocampal tissue from 40 neurologically healthy adults aged 20 to 95 years old, as detailed in a … Read more

New Vitamin B12 Therapy Shows Promise Against Deadly Brain Cancer

Researchers have identified a modified form of vitamin B12, known as nitrosylcobalamin (NO-Cbl), that can cross the blood-brain barrier to target glioblastoma tumors. A study published in Oncoscience by Joseph A. Bauer of Nitric Oxide Services, LLC and the Cleveland Clinic Foundation Taussig Cancer Center found that this compound selectively accumulates in brain cancer tissue, … Read more