US FDA Approves First Oral Cholesterol Pill to Replace Injections

The US Food and Drug Administration has approved Lipfendra, making it the world’s first oral PCSK9 inhibitor tablet designed to dramatically lower bad cholesterol for adults with high cholesterol conditions, including heterozygous familial hypercholesterolaemia, according to recent regulatory announcements. This milestone offers a daily pill alternative to injectable therapies, though the drug is not yet … Read more

J&J Highlights Spravato Remission Data to Drive TRD Growth

Esketamine, marketed by Johnson & Johnson as Spravato, has evolved from a niche add-on therapy into a primary monotherapy for treatment-resistant depression (TRD), with sales reaching $1.7 billion in 2024. Recent data presented at Psych Congress Elevate suggests that long-term remission rates for the drug may be more durable than previously documented in clinical literature, … Read more