Innatoss Laboratories starts test for the detection of neutralizing antibodies with the cPass kit from GenScript against SARS-CoV-2 in Europe

Leiden, the Netherlands, and Oss, the Netherlands and Piscataway, New Jersey, Jan. 29 / PRNewswire / – cPass is the first commercially available product for the rapid detection of virus-neutralizing antibodies

Innatoss Laboratories (https://apc01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.innatoss.com%2Fen%2F&data=02%7C01%7CBerkan.Unal%40genscript.com%7C82302e2804b6462badcb08d85b% 7Cdc65b2eb97864a0e9fed90b43a77c777% 7C1% 7C0% 7C637359715791846676 & sdata = 7ai9fkIhS942pqqTsd1q6yNWE4% 2BZf1s1rcneAbf14j0% in Europe announced the tests against the 2 nd blanket for the general public against the gene service. 2 SARS .protection.outlook.com /? url = http% 3A% 2F% 2F% 2Fwww.genscript.com & data = 02% 7C01% 7CBerkan.Unal% 40genscript.com% 7C82302e2804b6462badcb08d85b48dd1f% 7Cdc65b2eb97864a0e9fed90b43a77c777% 7C1% 7C0% 7C637359715791856667 & sdata = FZpi02rLZILAgCfjz7df7oI% 2BuSPLYlUCDq43HOJ5YpE% 3D & reserved = 0) cPass SARS-CoV-2 detection kit for neutralizing antibodies (https://apc01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.genscript.com%2Fcovid-19-detection- svnt.html & data = 02% 7C01% 7CBerkan.Unal% 40genscript.com% 7C82302 e2804b6462badcb08d85b48dd1f% 7Cdc65b2eb97864a0e9fed90b43a77c777% 7C1% 7C0% 7C637359715791856667 & sdata = ofeqFYiPzSzkmQQrWv97WthxoX is used. The test kit is the first worldwide that enables the rapid detection of neutralizing antibodies (NAbs); these NAbs are found in the serum of COVID-19 patients and are responsible for warding off the virus infection. Innatoss is the first medical laboratory in Europe to offer such a service to the general public.

“Our collaboration with GenScript is a critical step in bringing high quality, innovative products to market to combat the COVID-19 pandemic, which is a global public health threat,” said Dr. Anja Garritsen, CEO of Innatoss. “cPass uses a novel test method that can detect the presence of virus-specific neutralizing antibodies. The test would also be conceivable to determine the duration of potential immunity in individuals and thus in the general population, thus also determining the development of vaccines and monoclonal antibody therapies The test will become an important indicator for monitoring neutralizing antibody titers in the blood of individuals once vaccination is given. ”

A study recently carried out by Innatoss in the southern Dutch city of Kessel, which was hit hard by the first wave of COVID-19, determined the lifespan of binding antibodies compared to neutralizing antibodies in test subjects. The patients’ IgG and IgM levels were initially determined using a rapid test 2-4 months after infection and then repeated again 2-3 months later. The patient samples were then tested for neutralizing antibodies using the GenScript cPass kit. In 90 percent of the cases, binding antibody levels fell significantly over time, while functional antibodies (neutralizing antibodies) remained constant in 70 percent of the tests.

“The cPass test achieves reliable results that correspond to the gold standard in virology laboratories, the ‘Live SARS-CoV-2 Virus Neutralization Test’, without the need for a biosafety level 3 laboratory,” explained Dr. Linfa Wang, the inventor of cPass and director of the Emerging Infectious Disease Program at Duke-NUS Medical School in Singapore. “This novel test not only shows the individual’s history of infection, it can also provide information on how we can protect ourselves in the future.”

“This collaboration is a significant step forward as it provides valuable insights into potential immunity and gives institutions around the world better access to a reliable COVID-19 testing approach,” said Dr. Patrick Liu, CEO of GenScript.

About GenScript Biotech Corporation

GenScript Biotech Corporation is a global biotechnology group that applies its proprietary technologies in a variety of areas: from fundamental research in the life sciences to translational biomedical research to industrial synthetic products and cell therapy solutions. With its goal of improving the health of humans and nature through biotechnology, the company has developed first-class capacities and competencies for the production of biological reagents and active ingredients.

About Innatoss Laboratories

Innatoss is a research-focused diagnostics laboratory in the Netherlands that combines product development with performing cutting-edge diagnostics for individuals and the community. With its core competence in serology and T-cell biology, it covers all aspects of the immune response in infectious diseases. Innatoss focuses on infectious diseases with a complex immunological background such as Q fever and Lyme disease. The company’s mission to “recognize early! … and significantly reduce health problems associated with infectious diseases” has been expanded to include COVID-19 in view of the 2020 epidemic.

Logo – https://mma.prnewswire.com/media/1274339/Logo_Logo.jpg

Press contact:

GenScript Biotech Corporation
Jungsoo Park
jungsoo.park@genscript.com

Media Susan Thomas
Principal
Endpoint Communications
1-619-540-9195
susan@endpointcommunications.net

Innatoss Laboratories
Anja Garritsen
anja.garritsen@innatoss.com

Original content by: GenScript, transmitted by news aktuell
Original message: https://www.presseportal.de/pm/148417/4710951

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The court did not recognize the examination of the stadium in Kaliningrad as evidence of guilt

The Central District Court of Kaliningrad recognized the construction and technical examination as unacceptable evidence of the guilt of Amir Kushkhov and Sergey Tribunsky, accused of fraud, TASS reports citing the decision. The document was one of the main evidence of the prosecution in the case of theft of 752 million rubles allocated for the engineering preparation of the stadium in Kaliningrad for the 2018 World Cup.

“Recognize as unacceptable evidence a conclusion on the results of a construction and technical examination with field work as part of a criminal case,” the court said.

The criminal case against Amir Kushkhov and Sergey Tribunsky, accused of committing a crime under Part 4 of Art. 159 of the Criminal Code (fraud on a particularly large scale), was instituted in 2014. According to investigators, the accused entered into a conspiracy with members of the criminal community Summa Group LLC, created by the brothers Ziyavudin and Magomed Magomedov. From January to September 2014, they submitted documents to the Federal Treasury Department for the Kaliningrad Region signed between HPP OJSC and GKU KO RUZKS with inaccurate information about the volume, cost and compliance of the design documentation. Based on these documents, HPP transferred more than 752 million rubles that the partners stole.

More details about the investigation of the thefts during the construction of the “Baltic Arena” are in the article “Kommersant” “The stadium is standing, but it is going.”

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The court did not recognize the examination of the stadium in Kaliningrad as evidence of guilt

The Central District Court of Kaliningrad recognized the construction and technical examination as unacceptable evidence of the guilt of Amir Kushkhov and Sergey Tribunsky, accused of fraud, TASS reports citing the decision. The document was one of the main evidence of the prosecution in the case of theft of 752 million rubles allocated for the engineering preparation of the stadium in Kaliningrad for the 2018 World Cup.

“Recognize as unacceptable evidence a conclusion on the results of a construction and technical examination with field work as part of a criminal case,” the court said.

The criminal case against Amir Kushkhov and Sergey Tribunsky, accused of committing a crime under Part 4 of Art. 159 of the Criminal Code (fraud on a particularly large scale), was instituted in 2014. According to investigators, the accused entered into a conspiracy with members of the criminal community Summa Group LLC, created by the brothers Ziyavudin and Magomed Magomedov. From January to September 2014, they submitted documents to the Federal Treasury Department for the Kaliningrad Region signed between HPP OJSC and GKU KO RUZKS with inaccurate information about the volume, cost and compliance of the design documentation. Based on these documents, HPP transferred more than 752 million rubles that the partners stole.

More details about the investigation of the thefts during the construction of the “Baltic Arena” are in the article “Kommersant” “The stadium is standing, but it is going.”

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China announces successful return of new spacecraft prototypes

C.hina’s new spacecraft prototype returned to Earth “successfully” on Friday, according to the authorities. The Chinese space agency said that the spaceship had landed safely at the designated place. It was confirmed on site that the cabin structure was intact.

The “Long March 5B” rocket lifted off the Wenchang spaceport on the south Chinese island of Hainan on Tuesday in an unmanned spacecraft. Minutes later, the spaceship reportedly decoupled and reached the intended orbit. According to the space agency, it was two days and 19 hours in space and was undergoing a series of experiments. The return had proven its efficiency, such as heat resistance.

The return of a Chinese transport capsule to Earth, on the other hand, had failed on Wednesday. According to the Chinese space agency, there was an unspecified “anomaly”.

The People’s Republic also wants to become a major power in space travel. Among other things, she wants to put her own space station called Tiangong (Sky Palace) into operation in 2022 and also fly to the moon in the long term. Beijing’s goal is to send a Chinese astronaut to the moon for the first time in around ten years and to set up a station there.

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No evidence of immunity after coronavirus infection

EAccording to the World Health Organization (WHO), immunity after a overcome infection with the novel coronavirus has not been proven: “There is currently no evidence that people who have recovered from Covid-19 and have the antibodies are protected from a second infection The World Health Organization said in Geneva on Saturday. The organization warned that the issue of “immunity certificates” could even promote a further spread of the pandemic.

As of Friday, no study found “whether the presence of antibodies to Sars-CoV-2 in humans gives immunity to future infection with this virus,” it said in a statement.

Governments in some countries are considering issuing immunity certificates based on tests and detection of antibodies in the blood. This is to loosen curfews and allow gradual return to work to boost the economy.

Risk of transmission stopping

According to the WHO, the available scientific data do not allow an “immunity certificate” or a “safety certificate” to be issued. “People who think they are immune to a second infection because they have tested positive can disregard public health recommendations,” warned the WHO. Citing such certificates “could therefore increase the risk that the transfer will continue”.

The serological tests currently used would also have to “go through an additional approval to determine their accuracy and reliability”. Above all, they should make it possible to distinguish the immune response to the novel coronavirus from the antibodies that would be formed if one of the six previous coronaviruses were infected. Four of them are common and cause mild cough. The other two trigger the respiratory infections Sars and Mers.

“People infected with one or the other of these viruses could form antibodies that interact with the antibodies that are formed when infected with the Sars-CoV-2,” said the WHO. It is therefore imperative to be able to recognize and distinguish this.

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Challenge yourself (III): find the differences

Who has never playedfind the differences in an image. So we have chosen this game for the third challenge in quarantine days.

These photographs have been taken by journalists during the coronavirus crisis.Find out where the differences are: the image below is the original and in the upper one you have to doclickin the cut where you think the difference is.

First picture

Two wild boars cross a street during confinement

In this Reuters photo, two wild boars cross a street in Haifa (northern Israel). The image was taken after the government decreed confinement.

Look for the differences between these other two images

A young man with a mask by Santa Cruz de Tenerife

This photograph taken byAndrés Gutiérrez for the newspaperThe day shows a young man with a surgical mask on a street in Santa Cruz de Tenerife during the state of alarm.

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Challenge yourself (II): imitate a painting

Surely during this quarantine more than one has made virtual visits to exhibitions and museums. To discover new works or contemplate your favorite paintings.

In our second challenge, we test your artistic knowledge. In the memorization game below there are fourfamous pictorial works.You have tomatch in less than a minute the two images that complete each of the four boxes. To play!

Imitate famous paintings: a viral challenge

It is clear that the imagination has no limits. We are checking it during confinement, both in Spain and in other countries of the world.

One of the most original initiatives and that is having a great impact on social networks is that ofimitate famous paintings, that is, do the pose anddress likeThe girl of the pearl, by Johannes Vermeer, for example, and posting the photo to Instagram. The initiative was born in the Netherlands when the quarantine began. They openedthis profile on instagram, which has 531 publications and 231,000 followers, and has gone viral throughout the internet universe.

Below, we select three imitations that have caught our attention:

The kiss (Gustav Klimt)

The Last Supper (Leonardo da Vinci)

Guernica (Pablo Ruiz Picasso)

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FDA approves COVID-19 test to be done at home, while in Miami they test people without symptoms – Telemundo Miami (51)

The COVID-19 diagnostic center at Charles Hadley Park in Miami-Dade County now extends its capacity to asymptomatic adults over 65. Located at 1350 NW and 50th Street, those interested should call 305 – 960 – 5050 to request an appointment.

But if you can’t get out of the house, the
US Food and Drug Administration, FDA,
authorizes home coronavirus testing.

The test, created by the Corporation of
Laboratorios de America, (LabCorp), can be done by the patient himself and
consists of collecting a nasal sample, using the self-collection kit of
LabCorp. It contains the appropriate cotton swabs for this type of
exam. Once finished, the patient must send their sample in a package
isolated, to the LabCorp laboratory for later analysis.

FDA Commissioner Stephen M. Hahn said
that this new coronavirus test variant is as reliable and safe as
those currently practiced in diagnostic sites.

These kits will be available to the population in the coming weeks at a cost of $ 119. The first LabCorp Kits will be for healthcare personnel and for emergency personnel.

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The FDA approves a kit to take the COVID-19 test at home – Telemundo San Antonio (60)

WASHINGTON – The Food and Drug Administration (FDA) approved this Tuesday a test that allows the diagnosis of COVID-19 through the study of samples obtained by patients themselves from home, They must then send them to a laboratory for analysis.

This was announced by this federal organization in a statement published on its website, in which it explains that this PCR test – that is, that looks for fragments of genetic material of the pathogen – developed by Laboratory Corporation of America (LabCorp) allows the study of samples Nasally collected by the patients themselves using a kit that has swabs and a saline solution.

Once patients collect the sample, they will have to send it in an isolated package to LabCorp, where it will be studied.

FDA Commissioner Stephen Hahn stressed the safety and effectiveness of the new test: “We work with LabCorp to ensure that the data obtained from the collection of samples from patients at home is as safe and accurate as the collection of samples in a doctor’s office, hospital, or other testing site. “

On its website, Pixel, a company owned by LabCorp, announces that the general consumer will be able to access this test in the coming weeks, although at the moment it will only be available to healthcare personnel, although its price is $ 119 for everyone.

In its statement, the FDA stresses that patients should only use the cotton swabs provided by LabCorp in the package that makes up the test, as there is concern about the possible cross contamination that could cause the use of cotton swabs other than those supplied .

Also, remember that this authorization does not mean that all the SARS-CoV-2 tests that can be performed at home have been authorized or will be.

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Italy tests a coronavirus contact tracking tool to speed up the way out of the crisis

MADRID

Updated:

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Applications that monitor possible contagions of Covid-19 coronavirus They are on the way to suffering a bubble. They have proliferated rapidly after prominent cases in South Korea or Singapore. Dozens of international organizations and governments have set their sights on this type of technological solutions with more or less success. But while a standard proposal is found, some countries are already testing their possibilities to flatten the curve. Italy, one of the main outbreaks of the pandemic, has started testing a contact tracking tool with the virus to speed up the shutdown exit.

Developed by the startup Bending Spoons, the proposal has been chosen by the Data Protection Authority of the country among the 319 tools presented in recent weeks. One of its highlights is that it will not work through GPS, the geolocation system of the mobile device, but through Bluetooth wireless technology. The data collected will be anonymous and, according to the authorities, should be deleted once the end of the pandemic alert state has been decreed.

As in other countries, this “app” will allow tracking those who have previously tested positive for the new coronavirus. This technology, which the citizen must use voluntarily, will function as a tool for self-assessment and self-protection regarding the positives. One way, to understand each other, to know at what moment a person has been exposed to an infected person.

Originally called Immuni, the application uses Bluetooth technology to record when users are close to each other. Thus, if someone tests positive for the coronavirus, the application could send an alert to users who have been in contact with the infected individual, recommending actions such as quarantine and virus testing while preserving anonymity.

Italy is the epicenter of the outbreak in Europe with the highest number of deaths (22,000 deaths) and second only to the United States. Although confinement was extended last week Until May 3, the government is looking for ways to reduce the restrictions imposed more than a month ago to curb the epidemic in order to revive the economy as soon as possible “We are working to test a contact tracking application in some Italian regions” , recognized this Thursday in statements to the RAI chain Domenico Arcuri, commissioner of Italy for the pandemic.

Smartphone apps and other technologies have been used in Asian countries such as Singapore and South Korea to help prevent new infections, but have raised some fear in Europe about their potential abuse in the processing of personal data and the possible invasion in privacy. In this sense, Arcuri referred to the controversy, arguing that the objective is for this application to spread throughout the country once the tests have been passed in the most affected regions. “It will be a mainstay in our strategy to deal with the post-emergency phase,” he added.

For approval, the Italian Ministry of Innovation launched a tender in March for developer companies to submit their proposals. The chosen one, finally, was the idea of ​​the company Bending Spoons, based in Milan, which develops applications of all kinds as a video editing tool. This project is part of the Pan-European Proximity Tracking Consortium to Preserve Privacy (PEPP-PT), an initiative that Spain has recently joined. This initiative is promoting a European platform to allow national contact tracking applications to “talk” to each other even among tourists crossing their borders.

Data protection experts believe that Bluetooth technology is a “more accurate and less intrusive way” to record the proximity and duration of illness in a contact compared to location tracking based on geolocation or satellites that have been used in some Asian countries. Italy has insisted that the application will be used voluntarily following the recommendations of the data protection regulator and the European privacy regulations. “We hope that our citizens will adopt it in a massive way, since their support is needed for the contact location system to work,” said Arcuri.

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