Adenine

Broken String Biosciences Launches BaseMap ABE for Base Editing Off-Target Analysis

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Broken String Biosciences has launched BaseMap ABE, a new platform designed to identify unintended off-target editing events in adenine base editing (ABE) applications. According to the company and reporting from OneNucleus, the tool uses INDUCE-seq technology to generate genome-wide data directly from biologically relevant cells rather than relying on prediction-based models. How BaseMap ABE Tracks … Read more

New Study Uncovers Metabolic Vulnerability in High-Risk Myelodysplastic Syndromes

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Researchers at the University of Colorado Anschutz Cancer Center have identified a metabolic weakness in the stem cells driving high-risk myelodysplastic syndromes, uncovering an unusual cellular energy dependency that could enable more targeted treatments for the aggressive blood cancer, according to a study published in Blood Cancer Discovery. NAD Dependence in High-Risk MDS Stem Cells … Read more

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