How Paternal Sperm Epigenetics Influences Early Pregnancy Loss

Texas A&M University researchers are investigating the paternal role in early pregnancy loss, shifting focus to sperm epigenetics and male fertility factors that affect over 50% of human conceptions and roughly half of cattle pregnancies. According to Lacey Luense, Ph.D., an assistant professor in the Texas A&M College of Agriculture and Life Sciences Department of … Read more

How Early-Life Stress Rewires the Brain for Future Sensitivity

New research published in the journal Neuron identifies a biological mechanism linking childhood adversity to lifelong stress hypersensitivity. By studying mouse models, scientists discovered that early-life stress (ELS) triggers epigenetic changes—specifically the enrichment of the H3K4me1 histone mark and the enzyme SETD7—within the brain’s ventral tegmental area (VTA), effectively priming dopamine neurons to overreact to … Read more