How Statins Trigger Muscle Pain Through Inflammatory Signals
New experimental research identifies how statins—widely used cholesterol-lowering medications—can trigger muscle atrophy and weakness by disrupting cellular metabolism and activating the NLRP3 inflammasome. According to findings published in recent experimental models, statins block the mevalonate pathway, leading to a shortage of isoprenoids and a subsequent loss of protein prenylation. This metabolic stress state activates inflammatory … Read more
