Lipoprotein

Updated ABCs Framework for Heart Disease Prevention

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The updated ABCs of cardiovascular disease (CVD) prevention framework, published in the American Journal of Preventive Cardiology in 2026, provides a standardized, evidence-based roadmap for clinicians to manage heart health across a patient’s lifespan. By integrating tools like the PREVENT™ risk scoring system and addressing Cardiovascular-Kidney-Metabolic (CKM) syndrome, the framework shifts clinical focus toward early, … Read more

How Statins Trigger Muscle Pain Through Inflammatory Signals

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New experimental research identifies how statins—widely used cholesterol-lowering medications—can trigger muscle atrophy and weakness by disrupting cellular metabolism and activating the NLRP3 inflammasome. According to findings published in recent experimental models, statins block the mevalonate pathway, leading to a shortage of isoprenoids and a subsequent loss of protein prenylation. This metabolic stress state activates inflammatory … Read more

New Blood Test Enhances HDL Function Analysis in Heart Disease

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Researchers at the Institute of Science Tokyo have developed a blood-based test that measures cholesterol efflux capacity (CEC), a key indicator of how well high-density lipoprotein (HDL) removes cholesterol from artery walls. Published in the journal Atherosclerosis, the study suggests that low CEC levels correlate with the presence of high-risk, lipid-rich coronary plaques, offering a … Read more

Healthy plant-based foods may improve pregnancy cardiometabolic markers

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Beyond “Plant-Based”: Why Quality is the New Gold Standard for Pregnancy Nutrition For years, the nutritional conversation around pregnancy has been binary: eat meat or go plant-based. However, emerging data is shifting the narrative. A recent analysis of NHANES (National Health and Nutrition Examination Survey) data suggests that for expectant mothers, what plants you eat … Read more

Scientists will probe whether processing itself makes ultra-processed foods harmful

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The Processing Paradox: Are Ultra-Processed Foods Inherently Harmful? For years, the conversation around ultra-processed foods (UPFs) has been relatively simple: avoid them to stay healthy. However, nutrition science is entering a more nuanced era. The central question shifting the landscape is whether these foods are dangerous given that of how they are made (industrial processing) … Read more

Elevated Lp(a) levels associated with residual cardiovascular risk

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Understanding the “Hidden” Heart Risk: What is Lipoprotein(a)? When most of us think about heart health, we focus on “bad” cholesterol, known as LDL. However, there is a more elusive particle in the blood that often flies under the radar: Lipoprotein(a), or Lp(a). View this post on Instagram about Elevated Lp, Lipoprotein From Instagram — … Read more

Eating oranges daily may shift lipid patterns in fatty liver disease

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Beyond the Plate: The Future of Fighting Fatty Liver with Precision Nutrition For decades, the medical advice for fatty liver disease was simple, if frustrating: “lose weight and eat better.” But as we move deeper into the era of personalized medicine, we are discovering that the fight against Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is … Read more

Evolocumab reduces cardiac events in high-risk diabetic patients

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Evolocumab: A New Era in Proactive Heart Disease Prevention? A groundbreaking analysis from the VESALIUS-CV trial, presented at the American College of Cardiology’s Annual Scientific Session, suggests a potential shift in how we approach heart disease prevention. The study reveals that evolocumab, a PCSK9 inhibitor, significantly reduced the risk of major cardiovascular events – by … Read more

Breast reduction surgery is linked to lower diabetes and heart risk

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Beyond Aesthetics: Could Breast Reduction Be a Metabolic Game Changer? For decades, breast reduction surgery has been recognized for its ability to alleviate physical discomfort and improve quality of life. But emerging research suggests this procedure may offer benefits that extend far beyond the cosmetic – potentially impacting long-term metabolic health. A recent study analyzing … Read more

Diabetic nephropathy shows severe biochemical abnormalities

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Diabetic Nephropathy: Unraveling Biochemical Abnormalities and Future Trends Chronic diabetes mellitus is increasingly recognized not just for its impact on blood sugar, but for its far-reaching consequences on multiple organ systems. A recent study highlights the complex biochemical disturbances associated with diabetic nephropathy (DNp), offering valuable insights into the disease’s progression and potential future diagnostic … Read more

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