Dual-Drug Microneedle Patch for Inflammation and Fat Browning

According to researchers at Wuhan University, more than 3 billion people worldwide currently suffer from obesity, a figure forecasted to exceed 4 billion by 2035. To combat weight rebound and inflammation-suppressed fat browning linked to single-agent therapies, scientists developed an adipose-targeted composite microneedle patch named LRSG-SG@MN, which co-delivers semaglutide and rosiglitazone to modulate immune response … Read more

Natural Hormone Suppresses Liver Inflammation via Brain-Gut Pathway

According to researchers at McMaster University, the naturally occurring hormone GDF15 protects the liver from inflammation and slows the progression of scarring through a brain-to-liver signaling pathway independent of weight loss. Published in Cell Metabolism, the findings challenge longstanding assumptions about the hormone, which is best known for suppressing appetite and promoting weight loss. Understanding … Read more