Parkinson’s Disease

Fat-producing enzyme identified as key driver of damage in Parkinson’s disease

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Parkinson’s Disease: A New Target in Fat Metabolism? A newly identified enzyme, glycerol-3-phosphate acyltransferase (GPAT), is emerging as a potential key player in the progression of Parkinson’s disease. Research from Nanyang Technological University, Singapore (NTU Singapore) suggests that GPAT’s role in fat production within brain cells could amplify the damage caused by the protein α-synuclein, … Read more

Rest tremor in Parkinson’s linked to better-preserved dopamine function

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Parkinson’s Tremor: A Latest Understanding and the Future of Treatment For decades, the link between Parkinson’s disease and dopamine loss has been a central tenet of understanding the condition. However, groundbreaking research from the University of Turku and Turku University Hospital in Finland is challenging this long-held belief, specifically regarding rest tremor – one of … Read more

Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria

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From Plastic Waste to Parkinson’s Treatment: A Revolution in Sustainable Pharma? A groundbreaking study published in Nature Sustainability details a remarkable feat of bioengineering: transforming discarded plastic into levodopa (L-DOPA), a crucial medication for managing Parkinson’s disease. Researchers have engineered Escherichia coli bacteria to “upcycle” poly(ethylene terephthalate) – commonly known as PET – into this … Read more

A longitudinal guide to early Parkinson’s progression

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Parkinson’s Disease: The Rise of Wearable Tech and Patient-Centric Research A new study published in the Journal of Neurology, and applauded by the Critical Path Institute (C-Path), highlights a significant shift in Parkinson’s disease (PD) research: a move towards longitudinal tracking of symptoms using wearable devices and a stronger emphasis on the patient experience. This … Read more

Boosting Tubulin Could Prevent Protein Clumping in Neurodegenerative Diseases

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The Brain’s Internal Rescue Team: How Tubulin Could Revolutionize Alzheimer’s and Parkinson’s Treatment For decades, Alzheimer’s and Parkinson’s diseases have been characterized by the build-up of toxic protein clumps – tau and alpha-synuclein – that wreak havoc on brain cells. But a groundbreaking discovery from Baylor College of Medicine is shifting the focus from simply … Read more

ATP delivery fixes dysfunctional dopamine packaging in Parkinson’s neurons

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Parkinson’s Disease: Latest Insights into Dopamine Dysfunction and Potential Therapies A groundbreaking study has revealed a critical link between energy deficiencies, impaired dopamine packaging, and the progression of Parkinson’s disease. Researchers at Ludwig-Maximilians-Universitaet Muenchen (LMU) have identified a mechanism where dysfunctional packaging of dopamine leads to toxic processes in neurons, but importantly, demonstrated that this … Read more

Parkinson’s Disease: Brain Network Identified for New Treatments

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Parkinson’s Disease: A Latest Understanding of the Brain’s Role For decades, Parkinson’s disease has been largely understood as a movement disorder. But, groundbreaking research is shifting this perspective, identifying a specific brain network as central to the disease’s wide-ranging symptoms. This discovery, led by researchers at China’s Changping Laboratory and Washington University School of Medicine … Read more

Two Genetic “Hits” Required to Trigger Parkinson’s Neurodegeneration

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The Two-Hit Theory of Parkinson’s: Why Some Risk Doesn’t Equal Disease For years, scientists have known that certain genes increase a person’s risk of developing Parkinson’s disease (PD). But why do some individuals with these genetic predispositions remain healthy, although others succumb to the debilitating effects of the condition? Groundbreaking research from Baylor College of … Read more

CSF DDC Levels Differentiate Parkinson’s Disease & Dementia with Lewy Bodies

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The Future of Dementia Research: A Novel Biomarker on the Horizon Researchers are making significant strides in understanding and diagnosing neurodegenerative diseases like Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB). A recent multi-center study, meticulously conducted across six cohorts and adhering to the stringent ethical guidelines of the Declaration of Helsinki, has spotlighted … Read more

Team pinpoints brain network responsible for Parkinson’s

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Parkinson’s Disease: A New Understanding of the Brain’s Role and Future Treatments For decades, Parkinson’s disease has been largely understood as a movement disorder. However, groundbreaking research is shifting this perspective, identifying a specific brain network – the somato-cognitive action network, or SCAN – as central to the disease’s development and symptoms. This discovery, led … Read more

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