Unstable Repeat DNA May Explain Missing Heritability in Mental Illness

Unstable Repeat DNA May Explain Missing Heritability in Mental Illness

Schizophrenia and bipolar disorder run in families with an 81 percent heritability rate in twin studies, yet standard genome-wide surveys have only uncovered about a quarter of that genetic risk. Researchers in Pune, India, propose that short, stuttering stretches of DNA largely overlooked by standard methods account for the missing inheritance, News-Medical reported. These repetitive … Read more