Tau Buildup in PSP Disrupts Brain Networks and Cognitive Function

Progressive supranuclear palsy (PSP) symptoms, including cognitive decline, may stem from remote brain network disruptions rather than just local tau protein accumulation. Research published in Science Advances by the National Institutes for Quantum Science and Technology (QST) indicates that tau deposits in deep brain regions can impair distant cortical areas, such as the prefrontal cortex, … Read more

Early Detection of Congenital Ventriculomegaly: Preventing Developmental Disabilities

New research published in Science Translational Medicine indicates that congenital cerebral ventriculomegaly (CCV)—a condition marked by fluid-filled brain ventricle swelling—is frequently linked to rare, damaging gene mutations. According to investigators at the Mass General Brigham Neuroscience Institute, these genetic findings suggest that CCV is often a marker of underlying neurodevelopmental disorders, including autism spectrum disorder, … Read more

How Histamine Boosts Memory, Decisions, and Learning

Beyond Dopamine: Why Histamine is the Next Frontier in Cognitive Enhancement For decades, the conversation around brain health and “smart drugs” has been dominated by two heavyweights: dopamine and serotonin. We talk about dopamine for motivation and serotonin for mood. But a groundbreaking shift is occurring in neurobiology, and it’s centering on a much older, … Read more

Early Alzheimer’s Detection: Brain Scans vs. Blood Tests

The Future of Alzheimer’s: Shifting from Late-Stage Reaction to Early Detection For decades, Alzheimer’s disease has been characterized as a diagnosis that arrives only after major symptoms manifest. However, the medical landscape is undergoing a paradigm shift. With new research published in The Lancet, the focus is moving toward detecting the disease years—or even decades—before … Read more