Researchers at The University of Texas MD Anderson Cancer Center have identified that resistance to tagraxofusp in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) is driven by severe mutations in the TET2 gene and reduced expression of the TXNRD1 enzyme. Published in the journal Leukemia, the study provides a potential framework for using these … Read more
A recent diphtheria outbreak in Australia’s Northern Territory resulted in 131 confirmed cases between January 2025 and April 2026, marking the region’s first significant local recurrence in two decades. According to a study published in Eurosurveillance, the outbreak was driven by the sequence type 381 strain, primarily affecting Aboriginal communities. While high childhood vaccination rates … Read more
Researchers at the University of São Paulo (USP) have identified 45 previously unknown toxins produced by Salmonella bacteria, a discovery that could influence future antibiotic development and biotechnology. The team, based at the Center for Research in Bacterial and Bacteriophage Biology (B3 RIDC), analyzed 6,165 Salmonella samples to map these microscopic “spear-like” defense systems. The … Read more