Efficacy

Customized mobile app intervention benefits older adults experiencing mild cognitive decline

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Revolutionizing Cognitive Health in Assisted Living: The Rise of Multidomain Interventions Recent studies underscore the potential of multidomain interventions in delaying or preventing cognitive decline among older adults in assisted living facilities. These interventions, which may include dietary improvements, puzzles, social interactions, and tech-based games and exercises, offer a proactive approach to cognitive health. Emerging … Read more

Engineered TIMPs show promise in fighting glioblastoma invasion

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Unveiling the Future of Brain Cancer Treatment: Engineered TIMPs as Potential Game Changers The fight against glioblastoma multiforme (GBM), one of the most aggressive forms of brain cancer, may be witnessing a breakthrough with the advent of engineered tissue inhibitors of metalloproteinases (TIMPs). A groundbreaking study published in Oncotarget Volume 16 on February 28, 2025, … Read more

New three-organ system offers an animal-free alternative for pharmacokinetics research

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The Revolution in Drug Testing: Organ-on-Chip Technology Organ-on-chip (OoC) technology is emerging as a groundbreaking approach to revolutionizing drug testing, particularly by minimizing reliance on animal testing. With recent advancements, such as the development of a three-organ system by Dynamic42, ESQlabs, Bayer, and the Placenta Lab at Jena University Hospital, the field is poised to … Read more

Review highlights next-generation cancer therapies targeting PIK3CA mutations

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Unlocking the Potential of PIK3CA: A Key Player in Cancer Therapy The PIK3CA gene, known for encoding the p110α subunit of phosphoinositide 3-kinase (PI3K), stands as one of the most frequently mutated oncogenes across various cancer types. The mutations within PIK3CA are pivotal in driving tumor progression, influencing metabolic pathways, and contributing to treatment resistance. … Read more

Can cognitive-behavioral therapy components be tailored to optimize ADHD treatment?

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Maximizing ADHD Treatment: The Future of Cognitive-Behavioral Therapy Attention-deficit hyperactivity disorder (ADHD) continues to present challenges in everyday life, workplace productivity, and interpersonal relationships. While medication remains a cornerstone for ADHD management, the spotlight on cognitive-behavioral therapy (CBT) components is growing due to their promising non-pharmacological potential. Recent studies have brought an exciting development by … Read more

Metronomic chemotherapy offers hope for children with neuroblastoma

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A Ray of Hope for Children: The Future of Metronomic Chemotherapy in Neuroblastoma Treatment Neuroblastoma, the most common extracranial solid tumor in children, presents a daunting challenge due to its advanced diagnosis in nearly 50% of cases. Despite treatment advancements, survival rates for high-risk and relapsed cases remain disheartening. In resource-limited settings, alternative therapies are … Read more

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