New Insights into the Brain-Immune Interaction: Potential for Treating Autoimmune Diseases

Groundbreaking research conducted by scientists at Columbia University’s Zuckerman Institute has unveiled a fascinating connection between the brain and the immune system. The study, conducted on mice, discovered that the brain possesses the remarkable ability to detect and regulate levels of inflammation within the body through a specific circuit involving the caudal nucleus of the solitary tract (cNST).

Inflammation is a critical part of our immune response. However, when it becomes dysregulated or excessive, it can contribute to various autoimmune diseases and inflammatory disorders. By identifying this brain-immune connection, researchers hope to develop innovative therapeutic strategies for managing these conditions.

Understanding the Brain Circuit Modulating Immune Responses

The study revealed that activating this specific brain circuit can significantly reduce inflammation. The potential therapeutic implications are enormous; targeting this circuit could provide new avenues for treating autoimmune diseases and inflammatory disorders.

“Similar to a thermostat, this newfound brain circuit helps increase or decrease inflammatory responses to keep the body responding in a healthy ma

Increasing case numbers show clear vaccination gaps. The Austrian Medical Association advocates expanding the public vaccination program.

Vienna (OTS) – “The topic of vaccination is currently of great importance to health policy for at least two reasons: On the one hand, the safety criteria for vaccination must not be weakened by professional groups such as pharmacists, who have a completely different training and specialization than doctors, suddenly being allowed to vaccinate without any medical supervision should. On the other hand, we are observing – current examples include measles and whooping cough – that diseases that were thought to have been overcome are returning,” said Johannes Steinhart, President of the Austrian Medical Association, summing up the current situation at a press conference today. The population’s high willingness to be vaccinated in the past has largely erased the importance of such diseases from public consciousness. “Therefore, more information needs to be provided about the high, often life-saving importance of vaccinations in order to increase willingness and vaccination coverage,” demanded Steinhart.

When it comes to vaccination, there is a central insight that must be emphasized again and again because it has far-reaching practical consequences for patient safety: “Vaccination is much more than just a jab,” said Steinhart, referring to the Austrian vaccination plan. This prescribes, for example, mandatory information and education about the disease to be prevented and the vaccination, an anamnesis and the determination of suitability for vaccination. And finally, follow-up observation plays an important role; this also requires suitable structural conditions. The strict standards of the Quality Assurance Ordinance apply to medical practices. “Whether the premises of pharmacies actually offer

The menstrual cycle is a physiological phenomenon which punctuates women’s lives and which is accompanied by numerous symptoms: fatigue, mood changes but also sometimes pain. Gold “It’s not normal to have pain during your period“ explains gynecologist Odile Bagot. In medical language, painful menstruation is called “dysmenorrhea“. Dysmenorrhea can be primary when it occurs in adolescence or secondary when it appears throughout the menstrual cycles. It can have several causes and be more or less disabling on a daily basis.

Ovarian pain

Pain may occur around theovulation i.e. around the 14th day for women who have 28 day cycles. We talk about “cyclical” pain. “If a woman presents with cyclical pain, the reflex will always be to analyze them in relation to the date of the period. This is the benchmark. The healthcare professional will then be able to relate them to menstruation or not” explains Dr. Bagot. Ovulation results in a small 2cm cyst that bursts. It can lead to “sensations” in women who feel a temporary discomfort. There is nothing to worry about. On the other hand, if ovulation is associated with significant pain during 2 to 3 days, you should talk to the doctor. “Sometimes we see ovaria

Don’t get so caught up in your work that you forget to check for these 11 warning signs of depression at work.

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Of course, today’s work with many factors “Work is a major cause of stress” we cannot deny it. Especially in the current economic situation. Pressure is another thing that causes many people to endure more stress than before. what these things Did you know that they all affect our mental health? This article therefore invites all readers to take a look at the 11 warning signs of work-related depression.

Warning signs Risk of depression from work

1. Feeling increasingly

5.53pm Pro-Gaza hunger strike in Princeton

A group of Princeton students have begun a hunger strike in solidarity with the Palestinians of Gaza. Students belonging to the Princeton Israeli Apartheid Divest group are calling on the New Jersey Ivy League university to withdraw investments from companies that indirectly aid Israel’s military actions in Gaza.

5.44pm Hamas: Netanyahu aims to derail the chances of a truce

A Hamas leader has accused Israeli Prime Minister Benjamin Netanyahu of multiplying his statements to the media in order to sabotage efforts to secure a truce. Hamas political bureau member Hossam Badran told AFP that his negotiators were currently discussing the ceasefire proposal submitted at the end of April internally and with other Palestinian armed groups, before returning to Cairo. , where indirect negotiations with Israel will take place. The mediators – Egypt, Qatar, the United States – are still waiting in Cairo for Hamas’ response to this offer of truce.

17:07 Israel to Hamas: agreement in a week or we enter Rafah

Israel has notified Hamas that if an agreement is not reached within a week, it will begin the operation in Rafah. The Wall Street Journal reports this citing Egyptian sources. The indiscretion was also picked up by Haaretz.

12.59 Al Jazeera: 7 dead in night raid in Rafah, 4 children

A night-time air attack on a house in northern Rafah caused 7 victims, including 4 children. Al Jazeera reports it. Even in eastern Rafah the Qatari broadcaster speaks of “an increase in air attacks and artillery bombardments”. Israeli military attacks have also intensified in some parts of northern Gaza, such as the Sheikh Ijlin neighbourhood, as well as in the center of the Strip, where eyewitnesses say there is “constant intense artillery shelling”, Al Jazeera claims

12.50 Organizer: we had no option but to cancel the conference at the State University

There was no other choice but to cancel the conference on Israel scheduled for May 7 at the University of Milan, according to the organizers: “We couldn’t have done otherwise”, underlined Alessandro Litta Modignani of the ‘Pro Israel’ association who had organized the event together with the Italy-Israel association of Savona. «The police headquarters informed the university that the meeting fr