Arthritis

Secukinumab Rapidly Reduces Hidden Joint Inflammation in Psoriasis Patients

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Secukinumab, an IL-17A inhibitor, significantly reduces subclinical enthesitis in patients with moderate-to-severe plaque psoriasis, according to a study published in the journal Skin. By targeting inflammation at the attachment points of tendons and ligaments before joint pain begins, this treatment may prevent irreversible structural damage associated with psoriatic arthritis (PsA), researchers from The Second Affiliated … Read more

TREM-1 Receptor: A Promising Therapeutic Target for Inflammatory Diseases

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The Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) is emerging as a critical amplifier of the human innate immune system, according to a review published in Current Molecular Pharmacology. Researchers from Cairo University and E-JUST University identify this receptor as a potential therapeutic target for inflammatory conditions ranging from sepsis to Alzheimer’s disease, though clinical … Read more

How Patient Organizations Improve Rheumatic Disease Support

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Patient-led initiatives are reshaping rheumatology care by addressing critical gaps in support, such as menopause management, career sustainability, and equitable access to physiotherapy. According to the European Alliance of Associations for Rheumatology (EULAR), these person-centred models—presented at the EULAR 2026 Congress—demonstrate that integrating lived experience into health policy and clinical practice leads to measurable improvements … Read more

Low Adherence to Treat-to-Target Strategies in Rheumatology

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For years, the gold standard for medical knowledge has been the randomized controlled trial (RCT). While these trials are essential, they often exist in a “perfect” environment that doesn’t always mirror the messy, complex reality of daily clinical practice. That is changing. As presented at the latest EULAR Congress, the integration of real-world evidence (RWE) … Read more

Fiber Supplement Reduces Knee Arthritis Pain in 6 Weeks

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The New Frontier of Pain Relief: Why the Gut is the Next Big Target in Osteoarthritis For decades, the medical community’s approach to chronic pain, particularly osteoarthritis, has been largely reactive. We have relied on non-steroidal anti-inflammatory drugs (NSAIDs) to mask symptoms or intensive physiotherapy to rebuild strength. However, a groundbreaking shift is occurring. We … Read more

Arthritis sufferers warned about 2 fruits as common arthritis pain triggers

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The Evolution of Arthritis Management: Beyond the Prescription Pad For millions living with arthritis, the daily reality is a grueling cycle of swelling, inflammation, and limited mobility. While a definitive cure remains elusive, the landscape of joint health is shifting. We are moving away from a one-size-fits-all medical approach toward a sophisticated blend of personalized … Read more

Scientists identify new inflammatory mechanism to treat chronic health conditions

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The Shift Toward Precision Inflammation Control For decades, the medical community has viewed inducible nitric oxide synthase (iNOS) primarily as a factory for nitric oxide. The prevailing assumption was that this protein drove inflammation through the chemicals it produced. However, groundbreaking research published in Nature Metabolism has revealed a hidden side to iNOS: it acts … Read more

Natural peptide PEPITEM shows promise in reducing arthritic joint swelling

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PEPITEM: A Potential Game-Changer in Arthritis Treatment? New research suggests a naturally occurring immunopeptide, PEPITEM, could offer a significant advancement in the treatment of inflammatory arthritis, potentially rivaling current standard-of-care options. Scientists at the University of Birmingham, who initially discovered PEPITEM and characterized the Adiponectin-PEPITEM pathway, have demonstrated promising results in both human and animal … Read more

Macrophage immune memory depends on lingering interferon gamma

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The Body’s Immune Memory: How Macrophages ‘Remember’ and What It Means for Autoimmune Diseases Our immune system isn’t just about reacting to threats; it’s about remembering them. For years, this “memory” was largely attributed to specialized cells like lymphocytes. However, a groundbreaking study from the University of California, Los Angeles (UCLA), published February 18 in … Read more

Electroacupuncture relieves pain-induced anxiety through prefrontal neural circuits

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The Future of Pain Management: Acupuncture, the Brain, and Emotional Wellbeing For decades, chronic pain has been treated primarily as a sensory issue. However, emerging research is revealing a far more complex picture – one where pain is deeply intertwined with emotional and neurological processes. A growing body of evidence suggests that addressing the emotional … Read more

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