How can sticky notes help us understand disease? | News | CORDIS

Chemical tags added to RNA are proving to be surprisingly influential, offering new approaches to the detection, diagnosis and treatment of disease. © European Union, 2025 Messenger RNA carries instructions for building proteins from our DNA to the cell’s ribosomes. Along the way, chemical tags are added to RNA, much like sticky notes added to … Read more


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New method isolates true transcription factor targets in tuberculosis bacteria

Unlocking the Secrets of Gene Expression: A New Era in Cellular Understanding For decades, scientists have grappled with the complexity of gene expression – the process by which cells read the instructions encoded in DNA to create proteins. Inside every cell, a cacophony of molecular signals collide, making it difficult to pinpoint the true drivers … Read more

Study maps how NF-κB regulates gene expression in cells

Unlocking the Secrets of Gene Regulation: A Recent Era in Disease Treatment Researchers are gaining unprecedented insight into the intricate mechanisms governing gene expression, potentially paving the way for revolutionary therapies targeting inflammation, immunity, and even cancer. A recent breakthrough, published in Science Advances, centers on a protein called Dorsal, a variant of nuclear factor-κB … Read more

Study sheds light on behavior of yeast cells in the gut

The Gut’s Tiny Factories: How Engineered Yeast Could Revolutionize Drug Delivery A groundbreaking study from North Carolina State University is shining a light on the potential of Saccharomyces boulardii, a common probiotic yeast, as a powerful recent drug delivery platform. Researchers are now able to map how this yeast behaves within the gut, opening doors … Read more

Engineers develop highly precise gene editor for safer cystic fibrosis treatments

Gene Editing Precision: A New Era for Cystic Fibrosis and Beyond A significant leap forward in gene-editing technology is offering renewed hope for individuals with cystic fibrosis (CF) and a broader range of genetic diseases. Researchers at the University of Pennsylvania and Rice University have refined a technique to edit individual genetic “base pairs” with … Read more

Embryonic reproductive cells reveal striking genomic architecture before development

The Genome’s Hidden Dance: New Insights into the Origins of Life Researchers have discovered a remarkable reshaping of genetic material in the embryonic precursors to sperm and egg cells. This previously unknown process, detailed in a recent study published in Nature Structural & Molecular Biology, could hold the key to overcoming major hurdles in infertility … Read more

New AI-based analysis method can accurately classify and monitor brain tumors

AI Revolutionizes Brain Tumor Diagnosis: A New Era of Precision and Early Detection A groundbreaking AI-powered tool, dubbed M-PACT (Methylation-based Predictive Algorithm for CNS Tumors), is poised to transform the diagnosis and monitoring of brain tumors. Developed by an international research team with key contributions from the Medical University of Vienna, St. Jude Children’s Hospital, … Read more

Genome sequencing data reveals new insights into Epstein-Barr virus immunity

Unlocking the Secrets of Epstein-Barr Virus: A New Era of Immunity Research For decades, the Epstein-Barr virus (EBV) has remained a significant medical enigma. Present in approximately 90-95% of the global adult population, EBV is linked to cancers like Hodgkin’s lymphoma and autoimmune diseases such as multiple sclerosis. Now, groundbreaking research from the University Hospital … Read more

Researchers identify a genetic brake for the formation of blood vessels in muscles

The Genetic Key to Endurance: How Understanding RAB3GAP2 Could Revolutionize Training and Metabolic Health A groundbreaking international study led by Lund University in Sweden has pinpointed a gene variant, RAB3GAP2, that significantly influences the body’s ability to build fresh blood vessels in muscles. This discovery isn’t just for elite athletes; it holds potential for personalized … Read more

A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer

Mitochondrial Breakthrough: Yeast Enzyme Offers New Hope for Rare Diseases and Cancer A recent study published in Nature Metabolism reveals a surprising link between mitochondrial function and nucleotide synthesis – the building blocks of DNA and RNA. Researchers have discovered that a yeast-derived enzyme, ScURA, can bypass the need for healthy mitochondria to produce these … Read more