How GLP-1 drugs affect the body beyond weight loss and glucose control

The Double-Edged Sword: Navigating the Risks of GLP-1 Weight Loss and Diabetes Drugs The booming popularity of drugs like semaglutide and tirzepatide, initially designed for type 2 diabetes, has surged thanks to their remarkable weight loss effects. But as millions embrace these medications, a clearer picture of their potential side effects and long-term risks is … Read more

Calibr-Skaggs and Kainomyx join forces to accelerate development of antimalarial drugs

Recent Alliance Targets Malaria’s Achilles’ Heel: The Parasite’s Skeleton A groundbreaking research collaboration between the Calibr-Skaggs Institute for Innovative Medicines at Scripps Research and Kainomyx, Inc. Promises a fresh approach to combating malaria. Supported by the Gates Foundation, the partnership focuses on disrupting the Plasmodium parasite’s cytoskeleton – a strategy that could unlock a new … Read more

Thermodynamic insights into histamine H1 receptor ligand binding

The Future of Drug Design: Beyond Binding Affinity to Enthalpy and Entropy For decades, drug discovery has largely focused on how tightly a molecule binds to its target. But a paradigm shift is underway, driven by a deeper understanding of the thermodynamic forces at play. Recent research, spearheaded by Professor Mitsunori Shiroishi at Tokyo University … Read more

Howard County schools spent $8M on GLP-1 weight-loss drugs — then pulled the plug

Weight-Loss Drugs and Employer Health Plans: A Growing Conflict The rising popularity of GLP-1 receptor agonist medications like Ozempic, Wegovy and Mounjaro is creating a financial strain on employer-sponsored health plans. The Howard County Public School System in Maryland recently announced it will significantly limit coverage of these drugs, a move mirroring a trend among … Read more

Addiction consults improve care for drug-related eye infections

The Intertwined Future of Ophthalmology and Addiction Care A recent study published in Ophthalmology Retina, led by Eric Gaier, MD, PhD, and Dean Eliott, MD, of Mass Eye and Ear, highlights a critical intersection: the link between injection drug utilize, eye infections, and access to addiction treatment. The research underscores a growing trend – recognizing … Read more

Rise in young drug abusers arrested in 2025, including a 12-year-old: CNB

Authorities report a concerning trend in drug abuse, with a notable increase in female offenders. Arrests of female drug abusers rose by 24 percent, from 478 in 2024 to 594 in 2025, according to recent data. Rising Female Involvement Although the majority of those arrested for drug offenses in 2025 – 81 percent – were … Read more

Why pressure from Trump probably won’t push up drug prices in France

The Global Drug Price War: Trump, Macron, and the Future of Pharma The recent clash between US President Donald Trump and French President Emmanuel Macron over drug prices isn’t simply a transatlantic spat. It’s a symptom of a much larger, evolving struggle over the cost of pharmaceuticals and the future of the global pharmaceutical industry. … Read more

TrumpRx promises lower drug prices but some are questioning that

TrumpRx: A New Era for Prescription Drug Pricing? The recently launched TrumpRx.gov website aims to connect consumers directly with prescription drug manufacturers, offering potentially lower prices on a limited selection of medications. While touted by the administration as a historic reduction in drug costs, the reality appears more nuanced. The site currently lists 43 brand-name … Read more

Preoperative factors predict persistent opioid use after surgery

Beyond the Incision: Predicting and Preventing Long-Term Opioid Use After Surgery For millions of Americans, surgery represents a necessary step towards better health. But increasingly, that step can lead to an unintended consequence: long-term opioid dependence. A recent study from the University of Pennsylvania School of Nursing sheds light on who is most vulnerable to … Read more

Artificial lung keeps patient alive after lung removal

The Future of Artificial Lungs: Beyond Emergency Transplants A recent breakthrough, detailed in the journal Med, showcases a novel total artificial lung (TAL) system successfully bridging a patient to transplant after a desperate bilateral pneumonectomy. This isn’t just a remarkable case study; it’s a glimpse into a future where artificial lungs move beyond emergency life … Read more