Researchers at the University of Geneva have successfully restored the defective respiratory protective barrier in cystic fibrosis patients, tackling a primary driver of chronic bacterial infections in one of Switzerland’s most common genetic diseases. According to a study published in the journal Communications Biology, scientists traced the core dysfunction to the abnormal activation of a … Read more
Scorpion venom peptides are emerging as targeted drug candidates for inflammatory pathways and hepatitis viruses, according to a recent review published in the journal iLIVER. Researchers summarized how these molecules, sourced from over 2,700 documented scorpion species, target receptor proteins and voltage-gated ion channels to treat chronic inflammatory and hepatic disorders without the broad toxicity … Read more
< div> The Single Cell Genomics Center at the Bigelow Laboratory for Ocean Sciences is entering a new era of leadership and technical capability under the joint direction of senior research scientists Nicole Poulton and Julia Brown, according to an announcement from the laboratory. As the only open-access facility globally offering specialized educational programs and … Read more
The Defense Advanced Research Projects Agency has awarded $1.7 million to launch a project developing a wireless DNA and RNA printer operating entirely inside living yeast cells, according to the University of California, Santa Barbara. Led by UCSB molecular biologist Max Wilson and a multi-university team named LUXCODE, the initiative aims to build a nucleic … Read more
According to a randomized clinical trial published in the journal Cell Metabolism, a very-low-carbohydrate ketogenic diet reduces liver fat and improves insulin sensitivity significantly more than Mediterranean or plant-forward diets when participants achieve a comparable 10% weight loss. Researchers found that dietary macronutrient composition independently alters metabolic responses, yielding a 67% reduction in hepatic triglycerides … Read more
Researchers at Ludwig Princeton have discovered that tumors can manipulate distant organs to evade the immune system, according to a study published in Cell Metabolism. Led by Yibin Kang and Yong Tang, the research demonstrates how cancer cells send signals across the body to alter fat metabolism in the liver and immune responses in CD8⁺ … Read more
Radiation exposure to the thymus during non-small cell lung cancer treatment is associated with worse outcomes in patients being treated for non-small cell lung cancer (NSCLC), according to a study published in the journal Annals of Oncology. Thymus Health and Radiation Risks in NSCLC Patients Until recently, the thymus was thought to be of little … Read more
According to researchers at ETH, repetitive DNA sequences previously dismissed as useless “junk DNA” actually function as a biological barcode system that helps chromosomes find each other during cell division. Lead author Lena Skrutl and Professor Madhav Jagannathan published these findings in the journal Nature Communications, demonstrating that unique satellite DNA patterns on matching chromosome … Read more
Rare CD4 cytotoxic T lymphocytes reach strikingly high levels in people who live beyond 110, revealing an unusual pattern of clonal expansion and functional flexibility, according to a study published in the journal Cell Reports. Researchers characterising these immune cells found that supercentenarians maintain immune profiles that exhibit advanced differentiation without the typical markers of … Read more
Neurogenesis in the adult brain hippocampus stalls in patients with major depressive disorder, according to a study published by researchers at Columbia University Vagelos College of Physicians and Surgeons. While previous medical models linked depression primarily to neurotransmitter deficiencies like serotonin, the new findings indicate that the condition stems from broader issues affecting neuronal adaptability … Read more