Cell

How Cigarette Smoke Amplifies Nanoplastic Damage in Airway Cells

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According to a laboratory study published in Scientific Reports by researchers including D. Mirra and colleagues, cigarette smoke extract (CSE) compromises human airway epithelial barriers and increases cellular vulnerability to polystyrene nanoparticles (PS-NPs). The research team investigated how sequential exposure to these environmental stressors reduces cell metabolic activity and alters structural proteins in human bronchial … Read more

New Calcium Channel Discovery Opens Door to Brain Disorder Treatments

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Researchers at the Daegu Gyeongbuk Institute of Science and Technology (DGIST) have uncovered a molecular lever mechanism regulating the N-type voltage-gated calcium channel (CaV2.2), according to a study published in the July 2026 issue of the Proceedings of the National Academy of Sciences. Led by Professor Byung Chang Suh of the Department of Brain Sciences, … Read more

Key Barrier to Heart Cell Self-Repair Identified

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Cellular reprogramming to repair damaged heart tissue faces a major hurdle as scientists uncover how carbohydrate sulfotransferase 7 (CHST7) and CD44 receptors lock cellular identities in place, according to research published July 17, 2026, in Nature Communications by teams at the Sanford Burnham Prebys Medical Discovery Institute and The Johns Hopkins University School of Medicine. … Read more

Iodine and Immunity: How Balance Affects Your Immune System

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According to a narrative review published in the journal Nutrients by researchers at the University of Guelph and ImmunoCeutica Inc., iodine intake follows a narrow U-shaped relationship that dictates how the micronutrient influences immune defenses across humans and domesticated mammals. While adequate intake supports leukocyte metabolism and thyroid-driven immunity, both chronic deficiency and sustained excess … Read more

Genetic Susceptibility and Cancer Progression: What New Research Reveals

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Inherited genetics directly shape how our DNA interacts with acquired mutations to drive tumor evolution, according to research published in Nature. Scientists at the University of Cambridge and the University of Edinburgh found that an individual’s genetic background dictates both cancer risk and the specific evolutionary paths tumors take, offering new direction for precision medicine … Read more

Non-Endocytic Transmembrane Delivery for Precision Medicine

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Non-endocytic transmembrane delivery strategies are emerging to bypass canonical cellular uptake routes, directly addressing the low endosomal escape efficiency that has long hindered the clinical translation of therapeutic biomacromolecules like mRNA and gene-editing tools. According to a review published in Biomedical Analysis, these advanced platforms offer a direct path to the cytosol, potentially reshaping the … Read more

Genome Folding Linked to Alzheimer’s Brain Organization

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Researchers at Carnegie Mellon University, the University of Pittsburgh, and the University of Washington have mapped how 3D genome architecture differs in brain cells affected by Alzheimer’s disease. According to a study published in Science, the research team linked genome folding to gene activity and brain tissue organization using single-cell technology, spatial mapping, and a … Read more

How DNA Enhancer Hubs Drive Prostate Cancer Genes

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Researchers at the Keck School of Medicine of USC have identified a 3D hierarchy of DNA “enhancers” that function as master switches for prostate cancer development. According to a study published in Genome Biology, these interconnected networks control gene expression, revealing potential new targets for precision cancer therapies that could move beyond current gene-specific treatments. … Read more

UVA Researcher Wins Federal Grant to Study Rare Circulating Cells

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University of Virginia researcher Nathan Swami has secured a $1.1 million, four-year grant from the National Institutes of Health to develop microfluidic devices capable of identifying and isolating rare circulating cells. By integrating artificial intelligence with on-chip physical analysis, the project aims to improve diagnostic accuracy for cancer and infectious diseases by capturing cell subpopulations … Read more

Ultra-Processed Foods in Childhood Linked to Altered Insulin Response

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A study published in the journal Nutrients has linked high consumption of ultra-processed foods (UPFs) to early, measurable changes in insulin secretion and sensitivity among nondiabetic children. Researchers analyzed data from the San Antonio Family Assessment of Metabolic Risk Indicators in Youth (SAFARI) study, finding that higher UPF intake correlates with markers of insulin resistance … Read more

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